Publikationen 2020
Polymeric Nanoparticles with Neglectable Protein Corona
Irina Alberg, Stefan Kramer, Meike Schinnerer, Qizhi Hu, Christine Seidl, Christian Leps, Natascha Drude, Diana Möckel, Cristianne Rijcken, Twan Lammers, Mustafa Diken, Michael Maskos, Svenja Morsbach, Katharina Landfester, Stefan Tenzer*, Matthias Barz*, Rudolf Zentel
Small 907574 (2020)
An RNA Vaccine Drives Immunity in Checkpoint-Inhibitor-Treated Melanoma
Sahin, U.; Oehm, P.; Derhovanessian, E.; Jabulowsky, R. A.; Vormehr, M.; Gold, M.; Maurus, D.; Schwarck-Kokarakis, D.; Kuhn, A. N.; Omokoko, T.; Kranz, L. M.; Diken, M.; Kreiter, S.; Haas, H.; Attig, S.; Rae, R.; Cuk, K.; Kemmer-Brück, A.; Breitkreuz, A.; Tolliver, C.; Caspar, J.; Quinkhardt, J.; Hebich, L.; Stein, M.; Hohberger, A.; Vogler, I.; Liebig, I.; Renken, S.; Sikorski, J.; Leierer, M.; Müller, V.; Mitzel-Rink, H.; Miederer, M.; Huber, C.; Grabbe, S.; Utikal, J.; Pinter, A.; Kaufmann, R.; Hassel, J. C.; Loquai, C.; Türeci, Ö.
Nature 2020, 585 (7823), 107–112
The Influence of Nanoparticle Shape on Protein Corona Formation
Madathiparambil Visalakshan, R.; González García, L. E.; Benzigar, M. R.; Ghazaryan, A.; Simon, J.; Mierczynska-Vasilev, A.; Michl, T. D.; Vinu, A.; Mailänder, V.; Morsbach, S.; Landfester, K.; Vasilev, K.
Small 2020, 16 (25), 2000285.
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles
Wang, B.; Van Herck, S.; Chen, Y.; Bai, X.; Zhong, Z.; Deswarte, K.; Lambrecht, B. N.; Sanders, N. N.; Lienenklaus, S.; Scheeren, H. W.; David, S. A.; Kiessling, F.; Lammers, T.; De Geest, B. G.; Shi, Y.
J. Am. Chem. Soc. 2020, 142 (28), 12133–12139
Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of the tetrazine ligation for pretargeted nuclear imaging
E. J. L. Stéen, K. Nørregard, A. Birke, J. T. Jørgensen, K. Johann, D. Svatunek, P. E. Edem, R. Rossin, F. Schmid, H. Mikula, M. Robillard, J. L. Kristensen, M. Barz, A. Kjœr, M. M. Herth
ACS Nano 14, 568 (2020).
Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle–Cell Interactions
Dal, N. J. K.; Kocere, A.; Wohlmann, J.; Van Herck, S.; Bauer, T. A.; Resseguier, J.; Bagherifam, S.; Hyldmo, H.; Barz, M.; De Geest, B. G.; Fenaroli, F.
Small 2020, 16 (5), 1906719
Biology and Non-Invasive Biomarkers of Liver Fibrosis
Karsdal, M. A.; Daniels, S. J.; Holm Nielsen, S.; Bager, C.; Rasmussen, D. G. K.; Loomba, R.; Surabattula, R.; Villesen, I. F.; Luo, Y.; Shevell, D.; Gudmann, N. S.; Nielsen, M. J.; George, J.; Christian, R.; Leeming, D. J.; Schuppan, D. Collagen
Liver Int. 2020, 40 (4), 736–750
A Collagen-Binding Protein Enables Molecular Imaging of Kidney Fibrosis in Vivo
Baues, M.; Klinkhammer, B. M.; Ehling, J.; Gremse, F.; van Zandvoort, M. A. M. J.; Reutelingsperger, C. P. M.; Daniel, C.; Amann, K.; Bábíčková, J.; Kiessling, F.; Floege, J.; Lammers, T.; Boor, P.
Kidney Int. 2020, 97 (3), 609–614
Imidazoquinoline-Conjugated Degradable Coacervate Conjugate for Local Cancer Immunotherapy
Li, H.; Van Herck, S.; Liu, Y.; Hao, Y.; Ding, X.; Nuhn, L.; Zhong, Z.; Combes, F.; Sanders, N. N.; Lienenklaus, S.; Koker, S. D.; David, S. A.; Wang, Y.; De Geest, B. G.; Zhang, Z.
ACS Biomater. Sci. Eng. 2020, 6 (9), 4993–5000
Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for MRNA
Siewert, C. D.; Haas, H.; Cornet, V.; Nogueira, S. S.; Nawroth, T.; Uebbing, L.; Ziller, A.; Al-Gousous, J.; Radulescu, A.; Schroer, M. A.; Blanchet, C. E.; Svergun, D. I.; Radsak, M. P.; Sahin, U.; Langguth, P.
Cells 2020, 9 (9)
Multimodal and Multiscale Optical Imaging of Nanomedicine Delivery across the Blood-Brain Barrier upon Sonopermeation
May, J. N.; Golombek, S. K.; Baues, M.; Dasgupta, A.; Drude, N.; Rix, A.; Rommel, D.; Von Stillfried, S.; Appold, L.; Pola, R.; Pechar, M.; Van Bloois, L.; Storm, G.; Kuehne, A. J. C.; Gremse, F.; Theek, B.; Kiessling, F.; Lammers, T.
Theranostics 2020, 10 (4), 1948–1959
Microenvironmental Th9 and Th17 Lymphocytes Induce Metastatic Spreading in Lung Cancer
Salazar, Y.; Zheng, X.; Brunn, D.; Raifer, H.; Picard, F.; Zhang, Y.; Winter, H.; Guenther, S.; Weigert, A.; Weigmann, B.; Dumoutier, L.; Renauld, J. C.; Waisman, A.; Schmall, A.; Tufman, A.; Fink, L.; Brüne, B.; Bopp, T.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Huber, M.; Savai, R.
Clin. Invest. 2020, 130 (7), 3560–3575
Using Immuno-PET Imaging to Monitor Kinetics of T Cell-Mediated Inflammation and Treatment Efficiency in a Humanized Mouse Model for GvHD
Pektor, S.; Schlöder, J.; Klasen, B.; Bausbacher, N.; Wagner, D. C.; Schreckenberger, M.; Grabbe, S.; Jonuleit, H.; Miederer, M.
Eur. J. Nucl. Med. Mol. Imaging 2020, 47 (5), 1314–1325
Synthetic Rhamnose Glycopolymer Cell-Surface Receptor for Endogenous Antibody Recruitment
De Coen, R.; Nuhn, L.; Perera, C.; Arista-Romero, M.; Risseeuw, M. D. P.; Freyn, A.; Nachbagauer, R.; Albertazzi, L.; Van Calenbergh, S.; Spiegel, D. A.; Peterson, B. R.; De Geest, B. G.
Biomacromolecules 2020, 21 (2), 793–802
Inhibition of Antigen-Specific Immune Responses by Co-Application of an Indoleamine 2,3-Dioxygenase (IDO)-Encoding Vector Requires Antigen Transgene Expression Focused on Dendritic Cells
Sudowe, S.; Höhn, Y.; Renzing, A.; Maxeiner, J.; Montermann, E.; Habermeier, A.; Closs, E.; Bros, M.; Reske-Kunz, A. B.
Amino Acids 2020, 52 (3), 411–424
Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells
Schaupp, L.; Muth, S.; Rogell, L.; Kofoed-Branzk, M.; Melchior, F.; Lienenklaus, S.; Ganal-Vonarburg, S. C.; Klein, M.; Guendel, F.; Hain, T.; Schütze, K.; Grundmann, U.; Schmitt, V.; Dorsch, M.; Spanier, J.; Larsen, P. K.; Schwanz, T.; Jäckel, S.; Reinhardt, C.; Bopp, T.; Danckwardt, S.; Mahnke, K.; Heinz, G. A.; Mashreghi, M. F.; Durek, P.; Kalinke, U.; Kretz, O.; Huber, T. B.; Weiss, S.; Wilhelm, C.; Macpherson, A. J.; Schild, H.; Diefenbach, A.; Probst, H. C.
Cell 2020, 181 (5), 1080-1096.e19
Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules
Jiang S, Prozeller D, Pereira J, Simon J, Han S, Wirsching S, Fichter M, Mottola M, Lieberwirth I, Morsbach S, Mailänder V, Gehring S, Crespy D, Landfester K
Nanoscale. 2020 Jan 28;12(4):2626-2637.