Publikationen 2015

New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes

Bettina Krieg, Markus Hirsch, Erik Scholz, Lutz Nuhn, Ilja Tabujew, Heiko Bauer, Sandra Decker, Andriy Khobta, Manfred Schmidt, Wolfgang Tremel, Rudolf Zentel, Kalina Peneva, Kaloian Koynov, A. James Mason, Mark Helm

Pharmaceutical Research 32 (6), 1957–1974 (2015)

Fate of Linear and Branched Polyether-Lipids In Vivo in Comparison to Their Liposomal Formulations by 18F-Radiolabeling and Positron Emission Tomography

Achim T. Reibel, Sophie S. Müller, Stefanie Pektor, Nicole Bausbacher, Matthias Miederer, Holger Frey, Frank Rösch

Biomacromolecules 16 (3), 842–851 (2015)

Cylindrical Brush Polymers with Polysarcosine Side Chains: A Novel Biocompatible Carrier for Biomedical Applications

Christian Hörtz, Alexander Birke, Leonard Kaps, Sandra Decker, Eva Wächtersbach, Karl Fischer, Detlef Schuppan, Matthias Barz, Manfred Schmidt

Macromolecules 48 (7), 2074–2086 (2015)

How morphology influences relaxivity – comparative study of superparamagnetic iron oxide–polymer hybrid nanostructures

Sandro Ebert, Markus B. Bannwarth, Anna Musyanovych, Katharina Landfester, Kerstin Münnemann

Contrast Media & Molecular Imaging 10 (6), 456–464 (2015)

Natural liposomes and synthetic polymeric structures for biomedical applications

Laura K. Müller, Katharina Landfester

Biochem. Biophys. Res. Commun. 468 (3), 411–418 (2015)

IgG1 anti-epidermal growth factor receptor antibodies induce CD8-dependent antitumor activity

Jan Kubach, Mario Hubo, Christiane Amendt, Christopher Stroh, Helmut Jonuleit

Int. J. Cancer 136, 821–830 (2015)

Hybrid Poly(urethane–urea)/Silica Nanocapsules with pH-Sensitive Gateways

Matthew A. Hood, Umaporn Paiphansiri, David Schaeffel, Kaloian Koynov, Michael Kappl, Katharina Landfester, Rafael Muñoz-Espí

Chem. Mater. 27 (12), 4311–4318 (2015)

Fluorescence Correlation Spectroscopy in Dilute Polymer Solutions: Effects of Molar Mass Dispersity and the Type of Fluorescent Labeling

David Schaeffel, Stoyan Yordanov, Roland Hinrich Staff, Andreas Kreyes, Yi Zhao, Manfred Schmidt, Katharina Landfester, Johan Hofkens, Hans-Jürgen Butt, Daniel Crespy, Kaloian Koynov

ACS Macro Lett. 4 (2), 171–176 (2015)

Fluorescence Correlation Spectroscopy Monitors the Hydrophobic Collapse of pH-Responsive Hairy Nanoparticles at the Individual Particle Level

Jing Xie, Keita Nakai, Sayaka Ohno, Hans-Juergen Butt, Kaloian Koynov, Shin-ichi Yusa

Macromolecules 48 (19), 7237–7244 (2015)

CpG-loaded Multifunctional Cationic Nanohydrogel Particles as Self-Adjuvanting Glycopeptide Antitumor Vaccines

Sebastian Hartmann,⁺ Lutz Nuhn,⁺ Björn Palitzsch, Markus Glaffig, Natascha Stergiou, Bastian Gerlitzki, Edgar Schmitt, Horst Kunz, Rudolf Zentel

Adv. Health Care 4, 522–527 (2015)

Poly-l-lysine-poly[HPMA] block copolymers obtained by RAFT-polymerisation as polyplex-transfection reagents with minimal toxicity

Kristof Tappertzhofen, Franziska Weiser, Evelyn Montermann, Angelika Reske-Kunz, Matthias Bros^,* and Rudolf Zentel*

Macromol. Biosci. 15, 1159 –1173 (2015)

Not just for tumor targeting: Unmet medical needs and opportunities for nanomedicine

E. Lepeltier, L. Nuhn, C.M. Lehr*, R. Zentel*,

Nanomedicine 10 (20), 3147-3166 (2015)

In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles

Leonard Kaps, Lutz Nuhn, Misbah Aslam, Alexander Brose, Friedrich Foerster, Sebastian Rosigkeit, Patricia Renz, Rosario Heck, Yong Ook Kim, Ingo Lieberwirth, Detlef Schuppan* and Rudolf Zentel*

Adv. Health Care Materials, 4, 2809-2815 (2015)

The internal dynamics of fibrinogen and its implications for coagulation and adsorption

S. Köhler, F. Schmid, G. Settanni

PLOS Computational Biology 11, e1004346

Nanoparticles and antigen-specific T-cell therapeutics: a comprehensive study on uptake and release

O. Zupke, E. Distler, A. Jürchott, U. Paiphansiri, M. Dass, S. Thomas, U.F. Hartwig, M. Theobald, K. Landfester, V. Mailänder, W. Herr

Nanomedicine (Lond.) 2015, 10, 1063–1076

Heparin-Based Nanocapsules as Potential Drug Delivery Systems

G. Baier, S. Winzen, C. Messerschmidt, S. Frank, M. Fichter, S. Gehring, V. Mailänder, K. Landfester

Macromol. Biosci. 2015, 15, 765-776

Carbohydrate-Based Nanocarriers Exhibiting Specific Cell Targeting with Minimum Influence from the Protein Corona

B. Kang, P. Okwieka, S. Schöttler, S. Winzen, J. Langhanki, K.Mohr, T. Opatz, V. Mailänder, K. Landfester, F.R. Wurm

Angew. Chem. Internat. Ed. 2015, 54, 7436-7440

Nanoprobing the acidification process during intracellular uptake and trafficking

S. Lerch, S. Ritz, K. Bley, C. Messerschmidt, C.K. Weiss, A. Musyanovych, K. Landfester, V. Mailänder

Nanomedicine: nanotechnology, biology, and medicine 2015, 11, 1585-1596

Hematopoietic and mesenchymal stem cells: polymeric nanoparticle uptake and lineage differentiation

Brüstle, T. Simmet, G.U. Nienhaus, K. Landfester, V. Mailänder

Beilstein J. Nanotechnol. 2015, 6, 383-395.

Monophosphoryl lipid A coating of hydroxyethyl starch nanocapsules drastically increases uptake and maturation by dendritic cells while minimizing the adjuvant dosage

Fichter, M. Dedters, A. Pietrzak-Nguyen, L. Pretsch, C.U. Meyer, F. Zepp, G. Baier, K. Landfester, S. Gehring

Vaccine 2015, 7, 838-846

Complementary analysis of the hard and soft protein corona: sample preparation critically effects corona composition

Winzen, S. Schoettler, G. Baier, C. Rosenauer, V. Mailänder, K. Landfester, K. Mohr

Nanoscale 2015, 7, 2992-3001

Biodegradable Protein Nanocontainers

Piradashvili, M. Fichter, K. Mohr, S. Gehring, F.R. Wurm, K. Landfester

Biomacromolecules 2015, 16, 815-821

Tailoring the stealth properties of biocompatible polysaccharide nanocontainers.

B. Kang, P. Okwieka, S. Schöttler, O. Seifert, R. Kontermann, K. Pfizenmaier, A. Musyanovych, R. Meyer, M. Diken, U. Sahin, V. Mailänder, F.R. Wurm, K. Landfester

Biomaterials 2015, 49, 125-134

Protein corona of nanoparticles: distinct proteins regulate the cellular uptake

Ritz, S. Schöttler, N. Kotman, G. Baier, A. Musyanovych, J. Kuharev, K. Landfester, H. Schild, O. Jahn, S. Tenzer, V. Mailänder

Biomacromolecules 2015, 16, 1311-1321

Cellular uptake and in vitro antitumor efficacy of composite liposomes for neutron capture therapy

Peters T¹, Grunewald C, Blaickner M, Ziegner M, Schütz C, Iffland D, Hampel G, Nawroth T, Langguth P.

Radiat Oncol

Collaborative Research Center 1066

Nanodimensionale polymere Therapeutika für die Tumortherapie gefördert seit 2013 durch die DFG