Publikationen 2019

Smart cancer nanomedicine

van der Meel R, Sulheim E, Shi Y, Kiessling F, Mulder WJM, Lammers T.

Nat Nanotechnol. (2019) Nov;14(11):1007-1017.

JIF

Improved SiRNA Loading of Cationic Nanohydrogel Particles by Variation of Cross-Linking Density

Nadine Leber, Rudolf Zentel.

Macromol. Chem. Phys. 2020, 221.

The Role of Macrophages in Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

Kazankov, K.; Jørgensen, S. M. D.; Thomsen, K. L.; Møller, H. J.; Vilstrup, H.; George, J.; Schuppan, D.; Grønbæk, H.

Nat. Rev. Gastroenterol. Hepatol. 2019, 16 (3), 145–159

JIF

Visible Light Enables Aerobic Iodine Catalyzed Glycosylation

Krumb, M.; Lucas, T.; Opatz, T.

European J. Org. Chem. 2019, 2019 (28), 4517–4521

Nanomedicine and macroscale materials in immuno-oncology

Q Sun, M Barz, BG De Geest, M Diken, WE Hennink, F Kiessling, Twan Lammers, Yang Shi

Chemical Society Reviews 2019, 48 (1), 351-381

JIF

Nanotopography-Induced Unfolding of Fibrinogen Modulates Leukocyte Binding and Activation

Visalakshan, R. M.; Cavallaro, A. A.; MacGregor, M. N.; Lawrence, E. P.; Koynov, K.; Hayball, J. D.; Vasilev, K.

Adv. Funct. Mater. 2019, 29 (14), 1807453

JIF

From LC-Polymers to Nanomedicines: Different Aspects of Polymer Science from a Materials Viewpoint

Zentel, R.

Macromol. Chem. Phys. 2019, 220 (23)

Combining Nanomedicine and Immunotherapy

Shi, Y.; Lammers, T.

Acc. Chem. Res. 2019, 52 (6), 1543–1554

JIF

A Synthetic, Transiently Thermoresponsive Homopolymer with UCST Behaviour within a Physiologically Relevant Window

Zhang, Z.; Li, H.; Kasmi, S.; Van Herck, S.; Deswarte, K.; Lambrecht, B. N.; Hoogenboom, R.; Nuhn, L.; De Geest, B. G.

Angew. Chemie – Int. Ed. 2019, 58 (23), 7866–7872

Potent lymphatic translocation and spatial control over innate immune activation by polymer-lipid amphiphile conjugates of small molecule TLR7/8 agonists

Jana De Vrieze, Benoit Louage, Kim Deswarte, Zifu Zhong, Ruben De Coen, Simon Van Herck, Lutz Nuhn, Camilla Kaas Frich, Alexander N. Zelikin, Stefan Lienenklaus, Niek N. Sanders, Bart N. Lambrecht, Sunil A. David, Bruno G. De Geest

Angewandte Chemie International Edition 2019, 1900120

JIF

Water-Dispersed Semiconductor Nanoplatelets with High Fluorescence Brightness, Chemical and Colloidal Stability

Halim, H.; Simon, J.; Lieberwirth, I.; Mailänder, V.; Koynov, K.; Riedinger, A.; Simon, J.; Mailänder, V.

J. Mater. Chem. B 2019, 8 (1), 146–154

JIF

HPMA-Based Nanoparticles for Fast, Bioorthogonal IEDDA Ligation

Kramer, S.; Svatunek, D.; Alberg, I.; Gräfen, B.; Schmitt, S.; Braun, L.; Van Onzen, A. H. A. M.; Rossin, R.; Koynov, K.; Mikula, H.; Zentel, R.

Biomacromolecules 2019, 20 (10), 3786–3797

Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications

Dadfar SM, Roemhild K, Drude NI, von Stillfried S, Knüchel R, Kiessling F, Lammers T.

Adv Drug Deliv Rev. 2019, 138, 302-325

JIF

Noncovalent Targeting of Nanocarriers to Immune Cells with Polyphosphoester-Based Surfactants in Human Blood Plasma

Simon J, Bauer KN, Langhanki J, Opatz T, Mailänder V, Landfester K, Wurm FR

Adv Sci (Weinh). (2019) Oct 4;6(22):1901199.

JIF

Synthesis and Characterization of Bisalkylated Polysarcosine-Based Lipopolymers

Muhl, C.; Conrad, M.; Unthan, D.; Barz, M.

Eur. Polym. J. 2019, 120, 109223

Coordinative Binding of Polymers to Metal–Organic Framework Nanoparticles for Control of Interactions at the Biointerface

Zimpel, A.; Al Danaf, N.; Steinborn, B.; Kuhn, J.; Höhn, M.; Bauer, T.; Hirschle, P.; Schrimpf, W.; Engelke, H.; Wagner, E.; Barz, M.; Lamb, D. C.; Lächelt, U.; Wuttke, S.

ACS Nano 2019, 13 (4), 3884–3895

JIF

Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo

Ergen C, Niemietz PM, Heymann F, Baues M, Gremse F, Pola R, van Bloois L, Storm G, Kiessling F, Trautwein C, Luedde T, Lammers T, Tacke F.

Biomaterials. 2019, 206, 49-60.

JIF

Preparation of Monodisperse Giant Unilamellar Anchored Vesicles Using Micropatterned Hydrogel Substrates

Schultze, J.; Vagias, A.; Ye, L.; Prantl, E.; Breising, V.; Best, A.; Koynov, K.; Marques, C. M.; Butt, H. J.

ACS Omega 2019, 4 (5), 9393–9399

Unraveling In Vivo Brain Transport of Protein-Coated Fluorescent Nanodiamonds

Moscariello, P.; Raabe, M.; Liu, W.; Bernhardt, S.; Qi, H.; Kaiser, U.; Wu, Y.; Weil, T.; Luhmann, H. J.; Hedrich, J.

Small 2019, 15 (42), 1902992

JIF

DNA-Polymer Conjugates by Photoinduced RAFT Polymerization

Lueckerath, T.; Strauch, T.; Koynov, K.; Barner-Kowollik, C.; Ng, D. Y. W.; Weil, T.

Biomacromolecules 2019, 20 (1), 212–221

Ligand density on nanoparticles: A parameter with critical impact on nanomedicine

AM Alkilany, L Zhu, H Weller, A Mews, W Parak, M Barz, N Feliu

Adv Drug Deliv Rev. 2019 Mar 15;143:22-36.

JIF

Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

Wu, Y.; Li, L.; Frank, L.; Wagner, J.; Andreozzi, P.; Hammer, B.; D’Alicarnasso, M.; Pelliccia, M.; Liu, W.; Chakrabortty, S.; Krol, S.; Simon, J.; Landfester, K.; Kuan, S. L.; Stellacci, F.; Müllen, K.; Kreppel, F.; Weil, T.

ACS Nano 2019, 13 (8), 8749–8759

Transcutaneous Immunization with CD40 Ligation Boosts Cytotoxic T Lymphocyte Mediated Antitumor Immunity Independent of CD4 Helper Cells in Mice

Bialojan, A.; Sohl, J.; Rausch, J.; Aranda Lopez, P.; Denny, M.; Langguth, P.; Hartmann, A. K.; Yagita, H.; Probst, H. C.; Schild, H.; Radsak, M. P.

Eur. J. Immunol. 2019, 49 (11), 2083–2094

Possibilities and Limitations of Different Separation Techniques for the Analysis of the Protein Corona

C. Weber, S. Morsbach, K. Landfester

Angew. Chem. Intern. Ed. 10.1002/anie.201902323

JIF

Copper-Catalyzed Click Reactions: Quantification of Retained Copper Using 64Cu-Spiked Cu(I), Exemplified for CuAAC Reactions on Liposomes

Wagener, K.; Renisch, D.; Schinnerer, M.; Worm, M.; Jakob, Y.; Eberhardt, K.; Rösch, F.

Radiochim. Acta 2019, 107 (7), 547–554

Tackling the Limitations of Copolymeric Small Interfering RNA Delivery Agents by a Combined Experimental-Computational Approach

Tabujew, I.; Heidari, M.; Freidel, C.; Helm, M.; Tebbe, L.; Wolfrum, U.; Nagel-Wolfrum, K.; Koynov, K.; Biehl, P.; Schacher, F. H.; Potestio, R.; Peneva, K.

Biomacromolecules 2019, 20 (12), 4389–4406

Dermal CD207-Negative Migratory Dendritic Cells Are Fully Competent to Prime Protective, Skin Homing Cytotoxic T-Lymphocyte Responses

Hain, T.; Melchior, F.; Kamenjarin, N.; Muth, S.; Weslati, H.; Clausen, B. E.; Mahnke, K.; Silva-Vilches, C.; Schütze, K.; Sohl, J.; Radsak, M. P.; Bündgen, G.; Bopp, T.; Danckwardt, S.; Schild, H.; Probst, H. C.

J. Invest. Dermatol. 2019, 139 (2), 422–429

Polymer-Grafted Gold Nanoflowers with Temperature-Controlled Catalytic Features by: In Situ Particle Growth and Polymerization

Chen, C.; Ng, D. Y. W.; Weil, T.

Chem. Front. 2019, 3 (7), 1449–1453

CD11b Regulates Fungal Outgrowth but Not Neutrophil Recruitment in a Mouse Model of Invasive Pulmonary Aspergillosis

Teschner, D.; Cholaszczyńska, A.; Ries, F.; Beckert, H.; Theobald, M.; Grabbe, S.; Radsak, M.; Bros, M.

Front. Immunol. 2019, 10 (FEB), 123

Targeting Myeloid Cells in the Tumor Sustaining Microenvironment

Schupp, J.; Krebs, F. K.; Zimmer, N.; Trzeciak, E.; Schuppan, D.; Tuettenberg, A.

Cell. Immunol. 2019, 343

Impact of Branching on the Solution Behavior and Serum Stability of Starlike Block Copolymers

Holm, R.; Douverne, M.; Weber, B.; Bauer, T.; Best, A.; Ahlers, P.; Koynov, K.; Besenius, P.; Barz, M.

Biomacromolecules 2019, 20 (1), 375–388

A General Concept for the Introduction of Hydroxamic Acids into Polymers

Johann, T.; Keth, J.; Bros, M.; Frey, H.

Chem. Sci. 2019, 10 (29), 7009–7022

Investigation of Charge Ratio Variation in MRNA – DEAE-Dextran Polyplex Delivery Systems

Siewert, C.; Haas, H.; Nawroth, T.; Ziller, A.; Nogueira, S. S.; Schroer, M. A.; Blanchet, C. E.; Svergun, D. I.; Radulescu, A.; Bates, F.; Huesemann, Y.; Radsak, M. P.; Sahin, U.; Langguth, P.

Biomaterials 2019, 192, 612–620

JIF

GARP as an immune regulatory molecule in the tumormicroenvironment of glioblastoma multiforme

Zimmer N., Kim E., Sprang B., Leukel P., Khafaji F., Ringel F., Sommer C., Tuettenberg J, Tuettenberg A.

Int J Mol Sci. (2019). 20, 3676.

Dual Expression of GARP in Immune and Glioma Cells: Yet Another Mechanism of Cancer Immune Escape

Emily Trzeciak^1#, Niklas Zimmer^1#, Ella Kim^2,3, Jonathan Schupp¹, Bettina Sprang^2,3, Petra Leukel⁴, Fatemeh Khafaji⁵, Florian Ringel², Clemens Sommer⁴, Jochen Tuettenberg⁵, Andrea Tuettenberg^1*

J. Cell. Immunol. 2019, 1 (2)

Melatonin exerts oncostatic capacity and decreases melanogenesis in human MNT-1 melanoma cells

Kleszczyński K, Kim TK, Bilska B, Sarna M, Mokrzynski K, Stegemann A, Pyza E, Reiter RJ, Steinbrink K, Böhm M, Slominski AT.

J Pineal Res. (2019) Nov;67(4):e12610.

PI3K inhibition reduces murine and human liver fibrogenesis in precision-cut liver slices

Gore E, Bigaeva E, Oldenburger A, Kim YO, Rippmann JF, Schuppan D, Boersema M,
Olinga P.

Biochem Pharmacol. (2019) Nov; 169:113633.

Exploring organ-specific features of fibrogenesis using murine precision-cut tissue slices

Bigaeva E, Gore E, Mutsaers HAM, Oosterhuis D, Kim YO, Schuppan D, Bank RA,
Boersema M, Olinga P.

Biochim Biophys Acta Mol Basis Dis. 2020 Jan
1; 1866(1):165582.

Reactive ester derived nanogels for cancer immunotherapy

Judith Stickdorn, Lutz Nuhn

European Polymer Journal (2019).

A Synthetic Rhamnose Glycopolymer as Cell Surface Receptor for Endogenous Antibody Recruitment

Ruben Re Coen, Lutz Nuhn, Chamani Perera, Maria Arista Romero, Martijn Risseeuw, Alec Freyn, Raffael Nachbagauer, Lorenzo Albertazzi, Serge Van Calenbergh, David A. Spiegel, Blake R. Peterson, Bruno G. De Geest

Biomacromolecules (2019).

Polymer-Based Module for NAD+ Regeneration with Visible Light

Ma BC, Caire da Silva L, Jo SM, Wurm FR, Bannwarth MB, Zhang KAI, Sundmacher K, Landfester K.

Chembiochem. (2019) Oct 15;20(20):2593-2596.

Timing of Heparin Addition to the Biomolecular Corona Influences the Cellular Uptake of Nanocarriers

Champanhac C, Simon J, Landfester K, Mailänder V.

Biomacromolecules. (2019) Oct 14;20(10):3724-3732.

Covalently Binding of Bovine Serum Albumin to Unsaturated Poly(Globalide-Co-ε-Caprolactone) Nanoparticles by Thiol-Ene Reactions

Guindani C, Frey ML, Simon J, Koynov K, Schultze J, Ferreira SRS, Araújo PHH, de Oliveira D, Wurm FR, Mailänder V, Landfester K

Macromol Biosci. (2019) Oct;19(10):e1900145.

Isothermal titration calorimetry as a complementary method for investigating nanoparticle-protein interactions

Prozeller D, Morsbach S, Landfester K.

Nanoscale. (2019) Nov 7;11(41):19265-19273.

Overcoming the barrier of CD8+T cells: Two types of nano-sized carriers for siRNA transport

Tabujew I, Willig M, Leber N, Freidel C, Negwer I, Koynov K, Helm M, Landfester K, Zentel R, Peneva K, Mailänder V.

Acta Biomater. (2019) Dec;100:338-351.

Nanographenes: Ultrastable, Switchable, and Bright Probes for Super-Resolution Microscopy

Liu X, Chen SY, Chen Q, Yao X, Gelléri M, Ritz S, Kumar S, Cremer C, Landfester K, Müllen K, Parekh SH, Narita A, Bonn M

eCollection 2019. Review Angew Chem Int Ed Engl. 2020 Jan 2;59(1):496-502.

Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy

Saeed M, Gao J, Shi Y, Lammers T, Yu H.

Theranostics. (2019) Oct 17;9(26):7981-8000.

Evaluation of Charge-Regulated Supramolecular Copolymerization to Tune the Time-Scale for Oxidative Disassembly of ß-Sheet Comonomers

C.M. Berač, L. Zengerling, D. Straßburger, R. Otter, M. Urschbach, P. Besenius

Macromol. Rapid Commun. (2019), 1900476 Invited contribution to ‚100 years of polymer research‘ special issue.

Poly (Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes

Bleher S, Buck J, Muhl C, Sieber S, Barnert S, Witzigmann D, Huwyler J, Barz M, Süss R.

Small 15 (50), 1904716.

JIF

Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing: Implications for the design of improved nanoantibiotics

Siemer S, Westmeier D, Barz M, Eckrich J, Wünsch D, Seckert C, Thyssen C, Schilling O, Hasenberg M, Pang C, Docter D, Knauer SK, Stauber RH, Strieth S

Biomaterials 192, 551-559.

Precision Anisotropic Brush Polymers by Sequence Controlled Chemistry

Chaojian Chen, Katrin Wunderlich, Debashish Mukherji, Kaloian Koynov, Astrid Johanna Heck, Marco Raabe, Matthias Barz, George Fytas, Kurt Kremer, David Yuen Wah Ng, and Tanja Weil

Journal of the American Chemical Society (Cover Page).

How ill-defined constituents produce well-defined nanoparticles: Effect of polymer dispersity on the uniformity of copolymeric micelles

S Mantha, S Qi, M Barz, F Schmid

Physical Review Materials 3 (2), 026002.

Interactions Between Blood Proteins and Nanoparticles Investigated Using Molecular Dynamics Simulations

T Schafer, C Muhl, M Barz, F Schmid, G Settanni

High Performance Computing in Science and Engineering’18. p. 63-74

Against expectations: Unassisted RNA adsorption onto negatively charged lipid bilayers

Pannwitt S, Slama K, Depoix F, Helm M, Schneider D.

Langmuir. 2019 Oct 18

Die Nano-Bio-Grenzfläche: Analyse der Proteinkorona als Schlüssel für die biomedizinische Anwendung von Nanocarriern

Johanna Simon , Volker Mailänder, Katharina Landfester

GIT-Laborfachzeitschrift (2019)

Einführung in die Bio- und Medizinphysik In “Vielfältige Physik - Wissenschaftlerinnen schreiben über ihre Forschung

Katharina Landfester

Springer (2019), Weinheim, p. 265 – 271.

Polymeric Nanoparticles” in "Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches

B. Iyisan, K. Landfester

Springer Nature, Heidelberg p. 52 – 84

Modular Approach for the Design of Smart Polymeric Nanocapsules

B. Iyisan, K. Landfester

Macromol. Rapid Commun. 40, Art. No. 1800577

Prevention of Dominant IgG Adsorption on Nanocarriers in IgG-Enriched Blood Plasma by Clusterin Precoating

D. Prozeller, J. Pereira, J. Simon, V. Mailänder, S. Morsbach, K. Landfester

Adv. Sci. 6, Art. No. 1802199

JIF

Phosphonylation Controls the Protein Corona of Multifunctional Polyglycerol-Modified Nanocarriers

A.K. Danner, S. Schöttler, E. Alexandrino, S. Hammer, K. Landfester, V. Mailänder, S. Morsbach, H. Frey, F.R. Wurm

Macromol. Biosci. 19, Art. No. 1800468

Functionalization of Liposomes with Hydrophilic Polymers Results in Macrophage Uptake Independent of the Protein Corona

C. Weber, M. Voigt, J. Simon, A.K. Danner, H. Frey, V. Mailänder, M. Helm, S. Morsbach, K. Landfester

Biomacromolecules 20, 2989-2999

Functionalization of Liposomes with Hydrophilic Polymers Results in Macrophage Uptake Independent of the Protein Corona

C. Weber, M. Voigt, J. Simon, A.K. Danner, H. Frey, V. Mailänder, M. Helm, S. Morsbach, K. Landfester

Biomacromolecules 20, 2989-2999

Biomaterial Surface Hydrophobicity-Mediated Serum Protein Adsorption and Immune Responses

R.M. Visalakshan, M.N. MacGregor, S. Sasidharan, A. Ghazaryan, A.M. Mierczynska-Vasilev, S. Morsbach, V. Mailänder, K. Landfester, J.D. Hayball, K. Vasilev

ACS Appl. Mater. Interf. 11, 27615-27623

Using immuno-PET imaging to monitor kinetics of T cell-mediated inflammation and treatment efficiency in a humanized mouse model for GvHD

Pektor S, Schlöder J, Klasen B, Bausbacher N, Wagner DC, Schreckenberger M, Grabbe S, Jonuleit H, Miederer M.

Eur J Nucl Med Mol Imaging Aug 31

Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy

Renner K, Bruss C, Schnell A, Koehl G, Becker HM, Fante M, Menevse AN, Kauer N, Blazquez R, Hacker L, Decking SM, Bohn T, Faerber S, Evert K, Aigle L, Amslinger S, Landa M, Krijgsman O, Rozeman EA, Brummer C, Siska PJ, Singer K, Pektor S, Miederer M, Peter K, Gottfried E, Herr W, Marchiq I, Pouyssegur J, Roush WR, Ong S, Warren S, Pukrop T, Beckhove P, Lang SA, Bopp T, Blank CU, Cleveland JL, Oefner PJ, Dettmer K, Selby M, Kreutz M.

Cell Rep. Oct 1;29(1):135-150.e9

Evaluation of a novel monoclonal antibody against tumor-associated MUC1 for diagnosis and prognosis of breast cancer

Stergiou N, Nagel J, Pektor S, Heimes AS, Jäkel J, Brenner W, Schmidt M, Miederer M, Kunz H, Roesch F, Schmitt E.

Int J Med Sci. Aug 14;16(9):1188-1198

Core-Shell Functionalized Zirconium-Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content

B. Steinborn, P. Hirschle, M. Höhn, T. Bauer, M. Barz, S. Wuttke, E. Wagner, U. Lächelt

Adv Therapeutics 2019, 1900120

A microfluidic approach for sequential assembly of siRNA polyplexes with a defined structure – activity relationship

D.M. Loy, P.M. Klein, R. Krzysztoń, U. Lächelt, J.O. Rädler, E. Wagner

PeerJ Materials Science 2019, 1-37

Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions

L. Peng, E. Wagner

Biomacromolecules 2019, 20, 3613-3626

HPMA-Based Nanocarriers for Effective Immune System Stimulation

Stefan Kramer, Jens Langhanki, Matthias Krumb, Till Opatz, Matthias Bros, and Rudolf Zentel

Org. Macromol. Biosci. 2019, 19, 1800481

68Ga-, 111In-oxine: a novel strategy of in situ radiolabeling of HPMA-based micelles

Ana de la Fuente, Stefan Kramer, Nicole Mohr, Stefanie Pektor, Benedikt Klasen, Nicole Bausbacher, Matthias Miederer, Rudolf Zentel, Frank Rösch

Org. Am J Nucl Med Mol Imaging 2019, 9(1), 67–83

α-Mannosyl-Functionalized Cationic Nanohydrogel Particles for Targeted Gene Knockdown in Immunosuppressive Macrophages

Nadine Leber, Leonard Kaps, Aiting Yang, Misbah Aslam, Mariacristina Giardino, Sebastian Rosigkeit, Asmaa Mostafa, Lutz Nuhn, Detlef Schuppan, Rudolf Zentel

Org. Macromolecular Bioscience 2019, 19, 1900162

Engineering mannosylated nanogels with membrane-disrupting properties

Ruben De Coen, Lutz Nuhn, Bruno G. de Geest

Org. Polymer Chemistry 2019, 10, 4297-4304

Protein deglycosylation can drastically affect the cellular uptake

Ghazaryan, K. Landfester, V. Mailänder

Org. Nanoscale 2019, 11, 10727-10737

Supramolecular Assembly of Functional Peptide-Polymer Conjugates

R. Otter, P. Besenius

Org. Biomol. Chem. 2019, 17, 6719-6734

Investigation of α-amino acid N-carboxyanhydrides by X-ray diffraction for controlled ring-opening polymerization

O Schäfer, D Schollmeyer, A Birke, R Holm, K Johann, C Muhl, C Seidl, M. Barz

Tetrahedron Letters 2019, 60 (3), 272-275

The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis

Hansel C, Erschfeld S, Baues M, Lammers T, Weiskirchen R, Trautwein C, Kroy DC, Drescher HK.

Front Pharmacol. 2019, 10, 244.

Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis

Sun Q, Baues M, Klinkhammer BM, Ehling J, Djudjaj S, Drude NI, Daniel C, Amann K, Kramann R, Kim H, Saez-Rodriguez J, Weiskirchen R, Onthank DC, Botnar RM, Kiessling F, Floege J, Lammers T, Boor P.

Sci Transl Med. 2019, 11, 486.

Hyperthermia-triggered release of hypoxic cell radiosensitizers from temperature-sensitive liposomes improves radiotherapy efficacy in vitro

Sadeghi N, Kok RJ, Bos C, Zandvliet M, Geerts WJC, Storm G, Moonen CTW, Lammers T, Deckers R.

Nanotechnology. 2019,30, 26, 264001

CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell-Dependent Control of Senescence

Mossanen JC, Kohlhepp M, Wehr A, Krenkel O, Liepelt A, Roeth AA, Möckel D, Heymann F, Lammers T, Gassler N, Hermann J, Jankowski J, Neumann UP, Luedde T, Trautwein C, Tacke F.

Gastroenterology. 2019, 156, 6, 1877-1889

The CCR2+ Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers

Bartneck M, Schrammen PL, Möckel D, Govaere O, Liepelt A, Krenkel O, Ergen C, McCain MV, Eulberg D, Luedde T, Trautwein C, Kiessling F, Reeves H, Lammers T, Tacke F.

Cell Mol Gastroenterol Hepatol. 2019, 7, 2, 371-390.

3D-Bioprinted Mini-Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics

Heinrich MA, Bansal R, Lammers T, Zhang YS, Michel Schiffelers R, Prakash J.

Adv Mater. 2019, 31, 14, e1806590

Protein Corona Mediated Stealth Properties of Biocompatible Carbohydrate-based Nanocarriers

J. Simon, S. Christmann, V. Mailänder, F.R. Wurm, K. Landfester

Isr. J. Chem. 2018, 58, 1363 – 1372

High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis

S. Han, M. Raabe, L. Hodgson, J. Mantell, P. Verkade, T. Lasser, K. Landfester, T. Weil, I. Lieberwirth

Nanoletters 2019, 19, 2178-2185

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