Publikationen 2012/13

The chemotherapeutic agent topotecan differentially modulates the phenotype and function of dendritic cells

S. Trojandt, D. Knies, S. Pektor, S. Ritz, V. Mailänder, S. Grabbe, A. B. Reske-Kunz, M. Bros

Cancer Immunol Immunother 2013, 62, 1315–1326

A Trifunctional Dextran-Based Nanovaccine Targets and Activates Murine Dendritic Cells, and Induces Potent Cellular and Humoral Immune Responses In Vivo

L. Shen, T. Higuchi, I. Tubbe, N. Voltz, M. Krummen, S. Pektor, E. Montermann, K. Rausch, M. Schmidt, H. Schild, S. Grabbe, M. Bros

PLoS ONE 2013, 8, e80904

Interferon-α Suppresses cAMP to Disarm Human Regulatory T Cells

N. Bacher, V. Raker, C. Hofmann, E. Graulich, M. Schwenk, R. Baumgrass, T. Bopp, U. Zechner, L. Merten, C. Becker *, K. Steinbrink *

Cancer Res. 2013, 73, 5647-56

A versatile post-polymerization modification method for polyglutamic acid: synthesis of orthogonal reactive polyglutamates and their use in “click chemistry

M. Barz, A. Duro-Castano, M.J. Vicent

Polymer Chemistry, 2013, 4, 2989-2994.

Nanocapsules with specific targeting and release properties using miniemulsion polymerization

K. Landfester, V. Mailänder

Expert Opin. Drug Deliv. 2013, 10, 593-609

Complex encounters: nanoparticles in whole blood and their uptake into different types of white blood cells

D. Baumann, D. Hofmann, S. Nullmeier, P. Panther, C. Dietze, A. Musyanovych, S. Ritz, K. Landfester, V. Mailänder

Nanomedicine: Nanotechnology, Biology, and Medicine 2013, 8, 699-713

Polymeric nanoparticles of different sizes overcome the cell membrane

S. Lerch, M. Dass, A. Musyanovych, K. Landfester, V. Mailänder

Eur. J. of Pharmaceutics and Biopharmaceutics 2013, 84, 265-274

(Oligo)mannose functionalized hydroxyethyl starch nanocapsules: en route to drug delivery systems with targeting properties

H. Freichels, M. Wagner, P. Okwieka, R.G. Meyer, V. Mailänder, K. Landfester, A. Musyanovych

J. Mater. Chem. B 2013, 1, 4338-4348

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

S. Tenzer, D. Docter, J. Kuharev, A. Musyanovych, V. Fetz, R. Hecht, F. Schlenk, D. Fischer, K. Kiouptsi, C. Reinhardt, K. Landfester, H.J. Schild, M. Maskos, S. Knauer, R. Stauber

Nature Nanotechnology 2013, 8, 772 – 781

Nanocapsules generated out of a polymeric dexamethasone shell suppress the inflammatory response of liver macrophages

M. Fichter, G. Baier, M. Dedters, L. Pretsch, A. Pietrzak-Nguyen, K. Landfester, S. Gehring

Nanomedicine: Nanotechnology, Biology and Medicine, 2013, 9, 1223-1234

Absolute Quantitation of Sub-Micrometer Particles in Cells by Flow Cytometry

A. Höcherl, K. Landfester, V. Mailänder

Macromol. Biosci. 2013, 13, 1568-1575

Synthesis of Maleimide-Functionalyzed HPMA- Copolymers and in vitro Characterization of the aRAGE- and Human Immunoglobulin" (huIgG)–Polymer Conjugates

Kristof Tappertzhofen, Verena V. Metz, Mario Hubo, Matthias Barz, Rolf Postina, Helmut Jonuleit, Rudolf Zentel*

Macromol. Biosci. 13, 203- 214 (2013)

Combining Ring-Opening Multibranching and RAFT Polymerization: Multifunctional Linear-Hyperbranched Block Copolymers via Hyperbranched Macro Chain Transfer Agents

Lutz Nuhn, Christoph Schüll, Holger Frey* and Rudolf Zentel*

Macromolecules 46, 2892 -2904 (2013)

PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: A quantitative study using radiolabeling and Positron Emission Tomography

Mareli Allmeroth, Dorothea Moderegger, Daniel Gündel, Hans-Georg Buchholz, Nicole Mohr, Kaloian Koynov, Frank Rösch, Oliver Thews, Rudolf Zentel*

J. Controlled Release 172, 77 -85 (2013)

HPMA-LMA copolymer drug carriers in oncology: An in vivo PET study to assess the tumor line-specific polymer uptake and body distribution

Mareli Allmeroth, Dorothea Moderegger, Daniel Gündel, Kaloian Koynov, Hans-Georg Buchholz, Kristin Rausch, Frank Rösch, Rudolf Zentel, Oliver Thews *

Biomacromolecules 14, 3091–3101 (2013)

Water-Soluble Polymers Coupled with Glycopeptide Antigens and T-Cell Epitopes as Potential Antitumor Vaccines

Lutz Nuhn, Sebastian Hartmann, Bjçrn Palitzsch, Bastian Gerlitzki, Edgar Schmitt, Rudolf Zentel,* and Horst Kunz*

Angew. Chem. Int. Ed. 52, 10652 –10656 (2013)

Interaction of pHPMA-pLMA copolymers with human blood serum and its components

Mirjam Hemmelmann, Kristin Mohr, Karl Fischer, Rudolf Zentel* and Manfred Schmidt*

Mol. Pharmaceutics 10, 3769−3775 (2013)

Functionalized Polystyrene Nanoparticles Trigger Human Dendritic Cell Maturation Resulting in Enhanced CD4+ T Cell Activation

Stefanie U. Frick, Nicole Bacher, Grit Baier, Volker Mailänder, Katharina Landfester, Kerstin Steinbrink*

Macromol. Biosci. 2012, 12, 1637-1647

Sonderforschungsbereich 1066

Nanodimensionale polymere Therapeutika für die Tumortherapie gefördert seit 2013 durch die DFG