Publikationen 2014

Tailor-Made Nanocontainers for Combined Magnetic-Field-Induced Release and MRI

Bannwarth, S. Ebert, M. Lauck, M. Ziener, S. Tomcin, G. Jakob, K. Münnemann, V. Mailänder, A. Musyanovych, K. Landfester

Macromol. Biosci. 2014, 14, 1205 – 1214

Pharmacokinetics on a microscale: visualizing Cy5-labeled oligonucleotide release from poly(n-butylcyanoacrylate) nanocapsules in cells

Tomcin, G. Baier, K. Landfester, V. Mailänder

International Journal of Nanomedicine 2014, 9, 5471–5489

Glutathione-Responsive DNA-Based Nanocontainers Through an “Interfacial Click” Reaction in Inverse Miniemulsion

Paiphansiri, G. Baier, A. Kreyes, D. Yiamsawas, K. Koynov, A. Musyanovch, K. Landfester

Macromol. Chem. Phys. 2014, 215, 2457−2462

Evaluation of Multifunctional Liposomes in Human Blood Serum by Light Scattering

Kristin Mohr*, Sophie S. Müller*, Laura K. Müller, Kristiane Rusitzka, Sabine Gietzen, Holger Frey, and Manfred Schmidt

November 12, 2014 /in: Langmuir.

mRNA-based therapeutics--developing a new class of drugs

Ugur Sahin, Katalin Kariok, Özlem Türeci

2014 Oct;13 / Nat Reviews Drug Discovery

Imaging the intracellular degradation of biodegradable polymer nanoparticles

Anne-Kathrin Barthel, Martin Dass, Melanie Dröge, Jens-Michael Cramer, Daniela Baumann, Markus Urban, Katharina Landfester, Volker Mailänder, Ingo Lieberwirth

Beilstein J. Nanotechnol. 2014, 5, 1905-1917. published 29 Oct 2014.

Click Modification of Multifunctional Liposomes with Hyperbranched Polyether Chains

T. Fritz, M. Hirsch, F. C. Richter, S. S. Müller, A. M. Hofmann, U. Massing, H. Frey, M. Helm.

2014, Biomacromolecules, 15, 2440-2448

Cytotoxicity and Chemosensitizing Activity of Amphiphilic Poly(glycerol)–Poly(alkylene oxide) Block Copolymers

T.V. Demina, O. A. Budkina, G. A. Badun, N. S. Melik-Nubarov, H. Frey, S. S. Müller, J. Nieberle, I. D. Grozdova

2014, Biomacromolecules, 15, 2672-2681

Mass spectrometry and imaging analysis of nanoparticle-containing vesicles provide a mechanistic insight into cellular trafficking.

Hofmann, Daniel; Tenzer, Stefan; Bannwarth, Markus B; Messerschmidt, Claudia; Glaser, Simone-Franziska; Schild, Hansjorg; Landfester, Katharina; Mailander, Volker

ACS nano, Volume:8, Issue:10, Pages:10077-88

A Fully Synthetic Glycopeptide Antitumor Vaccine Based on Multiple Antigen Presentation on a Hyperbranched Polymer

Glaffig, B. Palitzsch, S. Hartmann, C. Schüll, L. Nuhn, B. Gerlitzki, E. Schmitt, H. Frey, H.Kunz,

Chem. Eur. J.2014, 15, 4232-4236

Quo Vadis Nanomedicine?

R. Luxenhofer, M. Barz, M. Schillmeier

Nanomedicine 2014, 9 (14), 2083-2086

Introducing PeptoPlexes: Polylysine-block-Polysarcosine Based Polyplexes for Transfection of HEK 293T Cells

Heller, A. Birke, D. Huesmann, B. Weber, K. Fischer, A. Reske-Kunz, M. Bros, M. Barz

Macromol Biosci 2014, 14, 1380–95

Synthesis and Sequential Deprotection of Triblock Copolypept(o)ides Using Orthogonal Protective Group Chemistry.

P. Heller, B. Weber, M. Barz.

Macromol Rapid Commun 2014

Directed Interactions of Block Copolypept(o)ides with Mannose-binding Receptors: PeptoMicelles targeted to Cells of the Innate Immune System.

P. Heller, N. Mohr, B. Weber, A. Birke, A. Reske-Kunz, M. Bros, M. Barz.

Macromol Biosci 2014

Aggregation Behavior of Cationic Nanohydrogel Particles in Human Blood Serum

Lutz Nuhn, Sabine Gietzen, Kristin Mohr, Karl Fischer, Kazuko Toh, Kanjiro Miyata, Yu Matsumoto, Kazunori Kataoka, Manfred Schmidt, and Rudolf Zentel

Biomacromolecules 15, 1526 -1533 (2014)

A Deeper Insight into the Postpolymerization Modification of Pentafluorophenylmetacrylates to Poly-N-(2-hydroxypropyl)-methacrylamide

Nicole Mohr, Matthias Barz*, Romina Forst, Rudolf Zentel*

Macromol. Rapid Commun. 35, 1461–1541 (2014)

Towards Anticancer Immunotherapeutics: Well-Defined Polymer-Antibody Conjugates for Selective Dendritic Cell Targeting

Kristof Tappertzhofen, Monika Bednarczyk, Kaloian Koynov, Matthias Bros, Stephan Grabbe and Rudolf Zentel*

Macromol. Biosci. 14,14, 1444–1457 (2014)

18F-Radiolabeling and Preliminary Evaluation of Folate-pHPMA Conjugates via PET

Hanno Schieferstein, Annette Kelsch, Achim Reibel, Kaloian Koynov, Matthias Barz, Hans-Georg Buchholz, Nicole Bausbacher, Oliver Thews, Rudolf Zentel*, Tobias L. Ross*

Macromol. Biosci. 14, 14, 1396–1405 (2014)

Degradable Cationic Nanohydrogel Particles for Stimuli-Responsive Release of siRNA

Lutz Nuhn*, Lydia Braun, Iris Overhoff, Annette Kelsch, David Schaeffel, Kaloian Koynov, Rudolf Zentel*

Macromol. Rapid. Commun. in press (2014)

Size-Dependent Knockdown Potential of siRNA-Loaded Cationic Nanohydrogel Particles

Lutz Nuhn, Stephanie Tomcin, Kanjiro Miyata, Volker Mailänder, Katharina Landfester, Kazunori Kataoka, Rudolf Zentel*

Biomacromolecules, 15, 4111-4121 (2014)

Novel cleavable cell-penetrating peptide– drug conjugates: synthesis and characterization

Marco Lelle, Stefanie U. Frick, Kerstin Steinbrink and Kalina Peneva

J. Peptide Sci. (2014), 20, 323-333

Selective Uptake of Cylindrical Poly(2-Oxazoline) Brush-AntiDEC205 Antibody-OVA Antigen Conjugates into DEC-Positive Dendritic Cells and Subsequent T-Cell Activation

Jasmin Bühler, Sabine Gietzen, Anika Reuter, Cinja Kappel, Karl Fischer, Sandra Decker, David Schäffel, Kaloian Koynov, Matthias Bros, Ingrid Tubbe, Stephan Grabbe, and Manfred Schmidt

ChemPubSoc

Aggregation Behavior of Polystyrene-Nanoparticles in Human Blood Serum and its Impact on the in vivo Distribution in Mice

Kristin Mohr, Maria Sommer, Grit Baier, Susanne Schöttler, Patricia Okwieka, Stefan Tenzer, Katharina Landfester*, Volker Mailänder, Manfred Schmidt and Ralf Georg Meyer

J Nanomed Nanotechnol 2014, 5:2

Selective Interfacial Olefin Cross Metathesis for the Preparation of Hollow Nanocapsules

Kerstin Malzahn, Filippo Marsico, Kaloian Koynov, Katharina Landfester, Clemens K. Weiss, and Frederik R. Wurm

ACS Macro Lett. 2014, 3, 40−43

Polymer Micro- and Nanocapsules as Biological Carriers with Multifunctional Properties

Anna Musyanovych, Katharina Landfester

Marcomolecular Bioscience

Interaction of N-(2-Hydroxypropyl)Methacrylamide Based Homo, Random and Block Copolymers with Primary Immune Cells

Martin Weilbächer, Mareli Allmeroth, Mirjam Hemmelmann, Sandra Ritz, Volker Mailänder, Tobias Bopp, Matthias Barz, Rudolf Zentel* and Christian Becker∗

J. Biomed. Nanotechnol. 10, 81 -91 (2014)

Revisiting Secondary Structures in NCA Polymerization: Influences on the Analysis of Protected Polylysines

D. Huesmann, A. Birke, K. Klinker, S. Türk, H.J. Räder, M. Barz

Macromolecules, 2014

Polypeptoid-block-Polypeptide copolymers: Synthesis, Characterization and Application of Amphiphilic "Block Copolypeptides in Drug Formulations and Miniemulsion Techniques"

A. Birke, D. Huesmann, A. Kelsch, M. Weilbacher, J. Xie, M. Bros, T. Bopp, C. Becker, K. Landfester, M. Barz

Biomacromolecules, 2014

Drug delivery without nanoparticle uptake: delivery by a kiss-and-run mechanism on the cell membrane

D. Hofmann, C. Messerschmidt, M. B. Bannwarth, K. Landfester, V. Mailänder

Chem. Commun. 2014, 50, 1369-71

Amino-functionalized nanoparticles as inhibitors of mTOR and inducers of cell cycle arrest in leukemia cells

C. Loos, T. Syrovets, A. Musyanovych, V. Mailänder, K. Landfester, T. Simmet

Biomaterials. 2014, 35, 1944-53

Sonderforschungsbereich 1066

Nanodimensionale polymere Therapeutika für die Tumortherapie gefördert seit 2013 durch die DFG